|
KMID : 0545120070170111880
|
|
Journal of Microbiology and Biotechnology
2007 Volume.17 No. 11 p.1880 ~ p.1884
|
|
|
Optimization of Antibacterial Activity by Gold-Thread (Coptidis Rhizoma Franch) Against Streptococcus mutans Using Evolutionary Operation-FactorialDesign Technique
|
|
Choi Ung-Kyu
Kim Mi-Hyang
Lee Nan-Hee
|
|
|
Abstract
|
|
|
|
This study was conducted to find the optimum extraction condition of Gold-Thread for antibacterial activity against Streptococcus mutans using The evolutionary operationfactorial design technique. Higher antibacterial activity was achieved in a higher extraction temperature (R2=-0.79) and in a longer extraction time (R2=-0.71). Antibacterial activity was not affected by differentiation of the ethanol concentration in the extraction solvent (R2=-0.12). The maximum antibacterial activity of clove against S. mutans determined by the EVOPfactorial technique was obtained at 80oC extraction temperature, 26 h extraction time, and 50% ethanol concentration. The population of S. mutans decreased from 6.110 logCFU/ml in the initial set to 4.125 logCFU/ml in the third set.
|
|
|
KEYWORD
|
|
|
Gold-Thread, EVOP-factorial design technique, antibacterial activity, S. mutans
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|